Blog Archives

Functional Genomics 2018 Annual Meeting

The 2018 annual meeting will be held April 9-10 at the University of Chicago Gordon Center for Integrative Sciences. The meeting will feature several scientific sessions, including presentations from senior personnel and trainees. Functional Genomics Project personnel, Steering Committee members,

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Gene network analysis identifies a central post-transcriptional regulator of cellular stress survival

The Crosson lab described a network-based approach to interrogate publicly available transcription data to predict genes that serve major functional roles in Caulobacter crescentus stress survival. This approach identified GsrN, a conserved small RNA whose expression is both necessary and

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Glutathionylation of Yersinia pestis LcrV and Its Effects on Plague Pathogenesis

The Schneewind lab identified the role of glutathionylation of Yersinia pestis LcrV, the cap protein of bacterial type III secretion needles. This modification contributes to the high virulence of Y. pestis in mouse and rat models for bubonic plague. Their

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Conserved ABC Transport System Regulated by the General Stress Response Pathways of Alpha- and Gammaproteobacteria

The Crosson lab defined the structure and function of a member of the conserved putative membrane transport system YehZYXW, whose expression is strongly activated by σE1 an EcfG family sigma factor that regulates the transcription of dozens of genes in

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2017 Functional Genomics Meeting

The 2017 Functional Genomics meeting will take place in Charleston, South Carolina on April 25-26.

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Next-Generation High-Throughput Functional Annotation of Microbial Genomes

A Functional Genomics publication describes the ways high-throughput functional genomics can lead to new therapeutics and better understanding of the next generation of emerging pathogens by rapidly defining new general mechanisms by which organisms cause disease and replicate in host

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2016 Functional Genomics Program meeting

The 2016 NIAID Functional Genomics program meeting will be hosted by Harvard University on May 2-4, 2016 in Boston, MA.

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First publication: A functional and structural analysis of B. abortus RicA

  The Crosson Lab has defined the B. abortus effector protein, RicA, as a carbonic anhydrase-like zinc metalloprotein.  This work was published in Biochemistry.

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