Technology Core

CCFA Biochemical Function Technology Core

 

Our research pipeline for function discovery is adding to our knowledge of hitherto uncharacterized gene products, and promoting a deeper understanding of the biology of Yersinia pestis and Brucella abortus.  At present, the de novo discovery of protein function for uncharacterized or hypothetical genes is a major challenge.  The CCFA Biochemical Function Technology Core led by Dr. Youngchang Kim of Argonne National Lab employs a workflow that is effective for the biochemical and biophysical characterization of gene products of unknown function, complementing in vivo functional characterization efforts of the Y. pestis and B. abortus research projects.

 

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